Fei Yu Postdoctor
Education and work Experience
2012-2016 Anhui Polytechnic University Bachelor
2016-2019 Anhui Polytechnic University Master
2019-2023 Jiangnan University Doctor
2024-now DICP CAS Postdoctor
Research Interest
Metabolic engineering of yeast and Streptomyces fradiae
Tel：0411-88133490 Email： yufei@dicp.ac.cn
Featured Publications
1. Yu F., Wang Z. W., Zhang Z. H., Zhou J. W., Li J. H., Chen J., Du G. C., Zhao X. R.*, Biosynthesis, acquisition, regulation, and upcycling of heme: Recent advances. Crit. Rev. Biotechnol., 2024, doi:10.1080/07388551.2023.2291339.
2. Yu F., Zhao X. R.*, Zhou J. W., Lu W., Li J. H., Chen J., Du G. C.*, Biosynthesis of high-active hemoproteins by the efficient heme-supply Pichia pastoris chassis, Adv. Sci., 2023,10, e2302826.
3. Yu F., Zhang M., Sun J. F., Wang F., Li X. F., Liu Y., Wang Z., Zhao X. R., Li J. H., Chen J., Du G. C.*, Xue Z. L.*, Improved neomycin sulfate potency in Streptomyces fradiae using atmospheric and room temperature plasma (ARTP) mutagenesis and fermentation medium optimization, Microorganisms, 2022,10, 94.
4. Li X. F.#, Yu F.#, Wang F., Wang S., Han R. M., Cheng Y. H., Zhao M., Sun J. F., Xue Z. L.*, Point mutation of V252 in neomycin C epimerase enlarges substrate-binding pocket and improves neomycin B accumulation in Streptomyces fradiae, Bioresour. Bioprocess., 2022, 9, 123.
5. Li X. F.#, Yu F.#, Liu K., Zhang M., Cheng Y. H., Wang F., Wang S., Han R. M., Xue Z. L.*, Uncovering the effects of ammonium sulfate on neomycin B biosynthesis in Streptomyces fradiae SF-2, Fermentation, 2022, 8, 678.
6. Yu F., Zhao X. R.*, Wang Z. W., Liu L. Y., Yi L. F., Zhou J. W., Li J. H., Chen J., Du G. C.*, Recent advances in the physicochemical properties and biotechnological application of Vitreoscilla hemoglobin, Microorganisms, 2021, 9, 1455.
Patent
1. Zhao X. R., Yu F., Zhou J. W., Du G. C., Chen J., Li J. H., Qian Y., Lu W., A method of constructing Pichia pastoris capable of synthesizing highly active heme-like proteins and its application thereof, No. PCT/CN2023/108903
2. Zhao X. R., Yu F., Zhou J. W., Du G. C., Chen J., Li J. H., Qian Y., Lu W., Construction and application of a chassis strain capable of synthesizing high-active hemoproteins, No. ZL202310773671.0
3. Wang Z. W., Zhao X. R., Zhou J. W., Yu F., Du G. C., Chen J., Li J. H., Construction of an efficient recombinant strain capable of synthesizing heme, No. ZL202210656237.X
4. Zhao X. R., Yu F., Wang Z. W., Zhou J. W., Du G. C., Chen J., Li J. H., Construction of an efficient recombinant strain capable of expressing myoglobin/hemoglobin from various sources, No. ZL202110607028.1
